Nano-Mite Technologies
The new mitochondrial uncoupler.
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.summary
Nano-Mite is a Game Changer
Nano-Mite Technologies LLC is a research company that has designed and patented nano-scale devices related to certain medical practices. Our most pressing and immediate goal is to address the problem of weight loss by designing nano tubes in such a manner that a person’s or animal’s metabolism can be manipulated and controlled yielding weight loss.Potential Health Benefits
- Reduces blood glucose levels
- Substantial weight loss
Humans & Animals
- Uncoupling Mitochondria is a Proven Way to Increase Metabolism and Cause Weight Loss
- We have Designed and Built Non-Carbon Based Nano-scale Devices that Self-Rectify themselves and Shut Off Before Comprising ATP Production
- Our Nano-scale Devices offer a Unique and Novel Approach to alter Metabolism
Future Goals
- Optimize Production Process for Large-Scale Production
- Move our Devices into other Larger Species
- Delivery methods: Patches, Injection, Oral?
- Optimize Production process for Large-Scale Production
- Move our Devices into other Larger Species
- Delivery Methods/Formulation: Patches, Injections, Oral?
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.accomplishments
Accomplishments
Timeline of Nano-Mite Technologies LLC and Accomplishments- Proof of concept studies completed demonstrating that nanotubes can be designed and built to be self-rectifying and safely uncouple mitochondria. This means that the concept of safely uncoupling mitochondria has been proven and that a working product has been built.
- Initial tests are positive and demonstrate that nanotubes can increase metabolism in rodents and cause significant weight loss and changes in weight gain. Experiments at the University of Kentucky have shown that a rodent’s metabolism can be manipulated safely to cause a weight loss.
- Proof of concept studies completed demonstrating that nanotubes can be designed and built to be self-rectifying and safely uncouple mitochondria. This means that the concept of safely uncoupling mitochondria has been proven and that a working product has been built.
- Initial tests are positive and demonstrate that nanotubes can increase metabolism in rodents and cause significant weight loss and changes in weight gain. Experiments at the University of Kentucky have shown that a rodent’s metabolism can be manipulated safely to cause a weight loss.
- Nano-Mite Technologies, LLC files provisional patent.
- Negotiated exclusive rights to license and market this technology with the University of Kentucky.
- In collaboration with the University of Kentucky, a non-provisional patent is filed in the USA and an international PCT is filed.
- The first of 4 US patents was granted April 5, 2011; # 7,919,699.
- Nano-Mite Technologies LLC was allowed office and laboratory space in the ASTeCC Incubator at the University of Kentucky. Only about 5% of the companies that request space at the ASTeCC Incubator are approved to locate there.
- Nano-Mite Technologies LLC chosen as the biotech company to represent the University of Kentucky at BIO 2007 in Boston. The International Biotechnology Organization (BIO) hosted the largest gathering in history of biotechnology companies with over 1,700 exhibitors and over 22,000 attendees at BIO 2007.
- Received a $25,000 ICC grant from the Kentucky Science and Technology Corporation to begin to implement mass production of nanotubes.
- Toxicity studies in canines began with outside company.
- Nanotubes built by Nano-Mite Technologies LLC were safely administered to canines without any toxicity reported at any dosage.
- Pre-clinical trials for weight reduction in obese canines begins in Spring of 2008. Results are positive and significant for weight loss.
- In Fall of 2008/Spring 2009 an IP disclosure was filed with UK covering the use of our product in the plant kingdom. Experiments are still ongoing with Dr. Robert Houtz in the College of Agriculture to determine the extent of this application.
- Current studies are underway in the laboratories of Nano-Mite Technologies LLC to further refine the production process and explore further opportunities for applications of our product.
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.market potential
Market Potential
Humans- U.S. annual health care costs spent due to obesity is $147 billion
- Well over 200 million Americans are in danger
- U.S. annual amount spent by consumers on weight loss is $60 billion
- Within 7 years U.S. health care amounts are forecasted to be in excess of $400 billion Statistics taken from:
- Currently U.S. market is $800 million a year Information provided by major pharmaceutical company
- U.S. Patent No. 7,919,699; Issue Date: 04/05/2011
“Nanotubes as Mitochondrial Uncouplers” - Australia Deed of Letters Patent 2006244374; Issue Date: 05/03/2012
“Nanotubes as Mitochondrial Uncouplers” - European Patent Convention, 06752314.2; Allowance Date: 06/14/2012
“Nanotubes as Mitochondrial Uncouplers” - U.S. Patent No. 8,357,845; Issue Date: 01/22/2013
“Nanotubes as Mitochondrial Uncouplers” - U.S. Patent No. 8,362,343; Issue Date: 01/29/2013
“Nanotubes as Mitochondrial Uncouplers”. - U.S. Patent No. 8,501,239; Issue Date: 08/06/2013
“Nanotubes as Mitochondrial Uncouplers”. - Canadian Intellectual Property Office; Allowance Date: 09/24/2013, “Nanotubes as Mitochondrial Uncouplers”.
– CNBC 2010 report “One Overweight Nation”
– Nature, (2011), 471: 569-571
Animals
Patents
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.project team